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Application of nanomaterials (silver and iron) in biomedicine

June 30,2020.
Nanotechnology has been successfully applied in China's medical field. A group in Nanjing used nano silver technology to develop and produce a medical dressing, a long-acting broad-spectrum antibacterial cotton. The production principle of this antibacterial cotton is to make silver into 20 nanometer ultrafine particles through nanotechnology, and then attach it to cotton fabric. Silver has the effect of preventing ulcers and accelerating wound healing. After the nanotechnology treatment, the surface of silver increases sharply, the surface structure changes, and the sterilization ability increases by about 200 times. It has a good inhibitory effect on clinical common surgical infections.
Nanoparticles and nanoparticles are used as drug delivery systems. The basic properties of the materials they produce are non-toxic, stable, good biological properties, and do not chemically react with drugs. Nanosystems are mainly used for the administration of drugs with high toxicity, short biological half-life, and easily degraded by enzymes.
Nanobiology is the study of biological processes on the nanoscale, and the development of molecular application engineering based on biological principles. After coating a layer of polymer with a thickness of 5-20 nanometers on the surface of the nano-iron powder, a large amount of proteins, especially enzymes, can be immobilized to control biochemical reactions. This is very useful in biochemical technology and enzyme engineering. Combining nanotechnology with biology, studying molecular biological devices, and using nanosensors, we can obtain biological information in the cell to understand the state of the body and deepen people's understanding of physiology and pathology.

In the 21st century, the demand for drugs is increasing. Controlling drug release, reducing side effects, improving drug efficacy and developing targeted drug therapies have been put on the research agenda. Nanoparticles will make drug delivery more convenient in the human body. Smart drugs encapsulated in the nano-iron powder layer enter the human body and can actively search for and attack cancer cells or repair damaged tissues. New diagnostic instruments using nanotechnology can diagnose various diseases by detecting a small amount of blood proteins and DNA. Using nano-magnetic material nano-iron powder as a drug carrier, a targeted drug was prepared. It is called "directional missile". The technology carries the drug on the surface of the protein coated with magnetic nano-iron particles, injects it into the blood vessels of the human body, and transports the drug to the lesion through the magnetic field navigation, and then releases the drug. Nano-iron powder has a small volume and can flow freely in blood vessels. It can be used to check and treat diseases in various parts of the body. The application of nanoparticles in clinical medicine and radiotherapy has also done a lot of research work.

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