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Nanotechnology is also a "double-edged sword"

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June 4,2025.

The 14th Shenzhen International Thermal and Heat Dissipation Materials and Equipment Exhibition (CIME2025)

The 14th Shenzhen International Thermal and Heat Dissipation Materials and Equipment Exhibition (CIME2025) will be held from June 4-6, 2025 at the Shenzhen International Convention and Exhibition Center. The exhibition area is 20000 square meters, wi...

May 29,2025.

Photothermal effect of anti-inflammatory and antioxidant properties Enhanced antibacterial hydrogel promotes infected wound healing

During the healing process of infectious wounds, bacterial infection, persistent oxidative stress, and long-term inflammation are the main obstacles. Developing a multifunctional wound dressing that can effectively eliminate bacteria, reduce oxidativ...

May 29,2025.

Ag2S nanodot based microneedle patch for postoperative melanoma recurrence and infectious trauma treatment

In the surgical treatment of malignant melanoma, incomplete tumor resection and extensive skin defects are the main reasons for high local recurrence rates and uncontrolled wound infections, leading to poor prognosis and prolonged patient recovery ti...

May 29,2025.

Light Stimulated Shuangluo gel for Photothermal Treatment of Cancer

Peptide substances have shown great potential in the field of biomaterials due to their high design flexibility, excellent biocompatibility, and degradability. Peptide based stimuli responsive biomaterials endow them with unique functions in drug del...

April 16,2025.

MXene regulates glycolysis for synergistic treatment of cancer

In recent years, treatment strategies targeting the unique metabolic characteristics of cancer cells, such as aerobic glycolysis, have gradually received attention. Among them, hunger therapy has shown potential therapeutic value by cutting off the g...

April 16,2025.

High air stability MXene biointerface thin film electrode

MXene exhibits excellent ion electron dual conductivity mechanism and has become a promising candidate material for biological interface electrodes. However, the exposed Ti atoms on the MXene layer are prone to oxidation in air, leading to severe deg...

April 16,2025.

Two dimensional tungsten based MXene material for hydrogen production by electrolysis of water

Electrolysis of water to produce hydrogen (HER) is the core technology for obtaining "green hydrogen", but existing precious metal catalysts (such as platinum) are expensive and difficult to apply on a large scale. Scientists are turning their attent...

January 9,2025.

The Chinese government supports the vigorous development of powder metallurgy enterprises

The powder metallurgy industry, as an important component of the new materials field, plays a crucial role in promoting the transformation and upgrading of China's manufacturing industry. Powder metallurgy technology, due to its unique process advant...

November 27,2024.

Rocket microneedle assisted deep drug delivery for combination therapy of melanoma

Melanoma is a highly invasive skin cancer, and its treatment faces challenges such as difficulty in penetrating the skin barrier with drugs and systemic side effects. As a unique transdermal drug delivery method, microneedles have many advantages suc...

November 27,2024.

CREKA Modified Silicone in the Treatment of bladder cancer

Bladder cancer, especially non muscle invasive bladder cancer (NMIBC), is the most common malignant tumor of the urinary system. Although cisplatin based chemotherapy has shown significant clinical efficacy as a first-line treatment, its therapeutic ...

Nanotechnology is also a "double-edged sword"

November 4,2018.
In our daily lives, nanotechnology will bring unexpected surprises to people. With nanometer (nm) coating, the refrigerator can be made into antibacterial, can be made into sterile tableware, can be made into self-cleaning glass and tiles without scrubbing. Using nanotechnology to make a micro drug delivery device, it can accurately reach the lesion site and reduce the adverse reactions of the drug.

Nanomaterials are made up of ultra-fine particles of less than 100 nanometers (nm) and are unique in size and function beyond imagination. Nanotechnology is also a "double-edged sword". While bringing convenience to life, it also has potential risks.

Environmental ecological risk of nanomaterials
Researchers have used nematode model organisms to find that nanomaterials that enter the environment can be transported along the food chain, accumulating in high-level organisms and exhibiting toxic effects. It not only causes damage to the parents, but also damages future generations. In addition, physical, chemical and biological transformations occur when nanomaterials enter the environment, which changes the physicochemical properties and ultimately affects the toxicity of nanomaterials.
Studies have found that ionic strength in the environment can dedicate nanosilver to release smaller nanoparticles. This small particle size nanosilver is more toxic than the original nanosilver. The pH in the water environment and the natural organic fulvic acid have similar effects.
"Aging" is another major change in the release of nanomaterials into the environment. Nano-zinc oxide undergoes morphological changes and changes in composition during the aging process of the water environment, and flakes appear around the particles. The research team used the latest technology to analyze the physicochemical transformation of nano zinc oxide in the water environment, and found that the newly formed material mainly contains basic zinc carbonate and zinc hydroxide.
At the same time, the study also found that the water environment aging process affects the toxicity of nano zinc oxide to chlorella. Researchers say that aging zinc oxide has low toxicity to chlorella, which is due to the physical and chemical transformation of nano-zinc oxide during the aging process of water environment, gradually producing low-toxic basic zinc carbonate and zinc hydroxide, which reduces the small The toxicity of chlorella.
Using mammalian cell model studies, it has also been found that the cytotoxicity of nano zinc oxide decreases with aging, but it is surprising that its neurite outgrowth is significantly enhanced. Studies have shown that the transformation of physicochemical properties of nano-zinc oxide with the aging time plays an important role in the induction of mammalian cytotoxic effects.

Nanomaterials combined with contaminants can produce complex toxicity
Due to the high specific surface area and unique surface chemistry of nanomaterials, when it enters the environment, it can be combined with a wide range of toxic pollutants, especially in water environments. Water is more active than soil and atmosphere. When artificial nanomaterials enter water, it is more prone to changes in agglomeration state, migration and chemical/biological transformation. That is to say, there are more opportunities for nanomaterials to interact with toxic pollutants. Researcher Wu Lijun said: "The composite effect between nanomaterials and pollutants will not only affect the environmental behavior and toxic effects of pollutants, but also have a significant impact on the physical and chemical properties and biological effects of nanomaterials themselves."
The researchers also cited another example of their research. Graphene oxide can reduce the cytotoxicity and genotoxicity of the organic pollutant polychlorinated biphenyl (PCB52) and play a role in cell self-defense. However, graphene oxide also has a strong adsorption and enrichment effect on heavy metal arsenic. Another higher yield of titanium dioxide also has a strong adsorption and enrichment effect on arsenic, while low concentration of titanium dioxide can significantly increase the toxicity of arsenic. These studies provide a new reference for the potential ecological risk assessment of nanomaterials.

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